Radiosynthesis and Initial In Vitro Evaluation of [(18)F]F-PEG(6)-IPQA—A Novel PET Radiotracer for Imaging EGFR Expression-Activity in Lung Carcinomas

INTRODUCTION: Epidermal growth factor receptor (EGFR)-targeted therapies with antibodies and small molecular EGFR kinase inhibitors have shown poor efficacy in unselected populations of patients with advanced non-small cell lung carcinomas (NSCLC). In contrast, patients with overexpression of EGFR a...

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Vydáno v:Mol Imaging Biol
Hlavní autoři: Pal, Ashutosh, Balatoni, Julius A., Mukhopadhyay, Uday, Ogawa, Kazuma, Gonzalez-Lepera, Carlos, Shavrin, Aleksandr, Volgin, Andrei, Tong, William, Alauddin, Mian M., Gelovani, Juri G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130206/
https://ncbi.nlm.nih.gov/pubmed/20859697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-010-0408-8
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