Pharmacokinetics, Metabolism, Biodistribution, Radiation Dosimetry, and Toxicology of (18)F-Fluoroacetate ((18)F-FACE) in Non-human Primates

INTRODUCTION: To facilitate the clinical translation of (18)F-fluoroacetate ((18)F-FACE), the pharmacokinetics, biodistribution, radiolabeled metabolites, radiation dosimetry, and pharmacological safety of diagnostic doses of (18)F-FACE were determined in non-human primates. METHODS: (18)F-FACE was...

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Detalhes bibliográficos
Main Authors: Nishii, Ryuichi, Tong, William, Wendt, Richard, Soghomonyan, Suren, Mukhopadhyay, Uday, Balatoni, Julius, Mawlawi, Osama, Bidaut, Luc, Tinkey, Peggy, Borne, Agatha, Alauddin, Mian, Gonzalez-Lepera, Carlos, Yang, Bijun, Gelovani, Juri G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902791/
https://ncbi.nlm.nih.gov/pubmed/21437735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-011-0485-3
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