Molecular imaging of active mutant L858R EGF receptor (EGFR) kinase-expressing nonsmall cell lung carcinomas using PET/CT

The importance of the EGF receptor (EGFR) signaling pathway in the development and progression of nonsmall cell lung carcinomas (NSCLC) is widely recognized. Gene sequencing studies revealed that a majority of tumors responding to EGFR kinase inhibitors harbor activating mutations in the EGFR kinase...

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Bibliographische Detailangaben
Hauptverfasser: Yeh, Hsin Hsien, Ogawa, Kazuma, Balatoni, Julius, Mukhapadhyay, Uday, Pal, Asutosh, Gonzalez-Lepera, Carlos, Shavrin, Aleksandr, Soghomonyan, Suren, Flores, Leo, Young, Daniel, Volgin, Andrei Y., Najjar, Amer M., Krasnykh, Victor, Tong, William, Alauddin, Mian M., Gelovani, Juri G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029752/
https://ncbi.nlm.nih.gov/pubmed/21220318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010744108
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