Synthesis and preliminary evaluation of [(18)F]-labeled 2-oxoquinoline derivatives for PET imaging of cannabinoid CB(2) receptor

INTRODUCTION: The cannabinoid receptor type 2 (CB2) is an important target for development of drugs and imaging agents for diseases, such as neuroinflammation, neurodegeneration, and cancer. Recently we reported synthesis and results of in vitro receptor binding of a focused library of fluorinated 2...

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Detalhes bibliográficos
Main Authors: Turkman, Nashaat, Paolillo, Vincenzo, Shavrin, Aleksander, Yeh, Hsin Hsien, Flores, Leo, Soghomonian, Suren, Ravinovich, Brian, Volgin, Andrei, Gelovani, Juri, Alauddin, Mian
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324652/
https://ncbi.nlm.nih.gov/pubmed/22226022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2011.10.019
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