Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks

BACKGROUND: The Ts1Cje mouse model of Down syndrome (DS) has partial triplication of mouse chromosome 16 (MMU16), which is partially homologous to human chromosome 21. These mice develop various neuropathological features identified in DS individuals. We analysed the effect of partial triplication o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ling, King-Hwa, Hewitt, Chelsee A, Tan, Kai-Leng, Cheah, Pike-See, Vidyadaran, Sharmili, Lai, Mei-I, Lee, Han-Chung, Simpson, Ken, Hyde, Lavinia, Pritchard, Melanie A, Smyth, Gordon K, Thomas, Tim, Scott, Hamish S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124147/
https://ncbi.nlm.nih.gov/pubmed/25052193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-624
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados