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Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks

BACKGROUND: The Ts1Cje mouse model of Down syndrome (DS) has partial triplication of mouse chromosome 16 (MMU16), which is partially homologous to human chromosome 21. These mice develop various neuropathological features identified in DS individuals. We analysed the effect of partial triplication o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ling, King-Hwa, Hewitt, Chelsee A, Tan, Kai-Leng, Cheah, Pike-See, Vidyadaran, Sharmili, Lai, Mei-I, Lee, Han-Chung, Simpson, Ken, Hyde, Lavinia, Pritchard, Melanie A, Smyth, Gordon K, Thomas, Tim, Scott, Hamish S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124147/
https://ncbi.nlm.nih.gov/pubmed/25052193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-624
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