Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks

BACKGROUND: The Ts1Cje mouse model of Down syndrome (DS) has partial triplication of mouse chromosome 16 (MMU16), which is partially homologous to human chromosome 21. These mice develop various neuropathological features identified in DS individuals. We analysed the effect of partial triplication o...

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Bibliografski detalji
Glavni autori: Ling, King-Hwa, Hewitt, Chelsee A, Tan, Kai-Leng, Cheah, Pike-See, Vidyadaran, Sharmili, Lai, Mei-I, Lee, Han-Chung, Simpson, Ken, Hyde, Lavinia, Pritchard, Melanie A, Smyth, Gordon K, Thomas, Tim, Scott, Hamish S
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124147/
https://ncbi.nlm.nih.gov/pubmed/25052193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-624
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