Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks

BACKGROUND: The Ts1Cje mouse model of Down syndrome (DS) has partial triplication of mouse chromosome 16 (MMU16), which is partially homologous to human chromosome 21. These mice develop various neuropathological features identified in DS individuals. We analysed the effect of partial triplication o...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ling, King-Hwa, Hewitt, Chelsee A, Tan, Kai-Leng, Cheah, Pike-See, Vidyadaran, Sharmili, Lai, Mei-I, Lee, Han-Chung, Simpson, Ken, Hyde, Lavinia, Pritchard, Melanie A, Smyth, Gordon K, Thomas, Tim, Scott, Hamish S
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124147/
https://ncbi.nlm.nih.gov/pubmed/25052193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-624
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires