SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer

Deregulation in lysine methylation signaling has emerged as a common etiologic factor in cancer pathogenesis, with inhibitors of several histone lysine methyltransferases (KMTs) being developed as chemotherapeutics(1). The largely cytoplasmic KMT SMYD3 (SET and MYND domain containing protein 3) is o...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mazur, Pawel K., Reynoird, Nicolas, Khatri, Purvesh, Jansen, Pascal W.T.C., Wilkinson, Alex, Liu, Shichong, Barbash, Olena, Van Aller, Glenn S., Huddleston, Michael, Dhanak, Dashyant, Tummino, Peter J., Kruger, Ryan G., Garcia, Benjamin, Butte, Atul J., Vermeulen, Michiel, Sage, Julien, Gozani, Or
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122675/
https://ncbi.nlm.nih.gov/pubmed/24847881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13320
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