Polymorphisms at Amino Acid Residues 141 and 154 Influence Conformational Variation in Ovine PrP

Polymorphisms in ovine PrP at amino acid residues 141 and 154 are associated with susceptibility to ovine prion disease: Leu141Arg154 with classical scrapie and Phe141Arg154 and Leu141His154 with atypical scrapie. Classical scrapie is naturally transmissible between sheep, whereas this may not be th...

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Hlavní autoři: Yang, Sujeong, Thackray, Alana M., Hopkins, Lee, Monie, Tom P., Burke, David F., Bujdoso, Raymond
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122135/
https://ncbi.nlm.nih.gov/pubmed/25126555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/372491
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