Argininosuccinate lyase in enterocytes protects from development of necrotizing enterocolitis

Necrotizing enterocolitis (NEC), the most common neonatal gastrointestinal emergency, results in significant mortality and morbidity, yet its pathogenesis remains unclear. Argininosuccinate lyase (ASL) is the only enzyme in mammals that is capable of synthesizing arginine. Arginine has several homeo...

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Bibliografiske detaljer
Main Authors: Premkumar, M. H., Sule, G., Nagamani, S. C., Chakkalakal, S., Nordin, A., Jain, M., Ruan, M. Z., Bertin, T., Dawson, B., Zhang, J., Schady, D., Bryan, N. S., Campeau, P. M., Erez, A., Lee, B.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2014
Fag:
Mucosal Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121640/
https://ncbi.nlm.nih.gov/pubmed/24904080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00403.2013
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