Chronic liver disease and impaired hepatic glycogen metabolism in argininosuccinate lyase deficiency

BACKGROUND: Liver disease in urea cycle disorders (UCDs) ranges from hepatomegaly and chronic hepatocellular injury to cirrhosis and end-stage liver disease. However, the prevalence and underlying mechanisms are unclear. METHODS: We estimated the prevalence of chronic hepatocellular injury in UCDs u...

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Publicat a:JCI Insight
Autors principals: Burrage, Lindsay C., Madan, Simran, Li, Xiaohui, Ali, Saima, Mohammad, Mahmoud, Stroup, Bridget M., Jiang, Ming-Ming, Cela, Racel, Bertin, Terry, Jin, Zixue, Dai, Jian, Guffey, Danielle, Finegold, Milton, Nagamani, Sandesh, Minard, Charles G., Marini, Juan, Masand, Prakash, Schady, Deborah, Shneider, Benjamin L., Leung, Daniel H., Bali, Deeksha, Lee, Brendan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Clinical Medicine
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101134/
https://ncbi.nlm.nih.gov/pubmed/31990680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.132342
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