Argininosuccinate lyase in enterocytes protects from development of necrotizing enterocolitis

Necrotizing enterocolitis (NEC), the most common neonatal gastrointestinal emergency, results in significant mortality and morbidity, yet its pathogenesis remains unclear. Argininosuccinate lyase (ASL) is the only enzyme in mammals that is capable of synthesizing arginine. Arginine has several homeo...

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Detalles Bibliográficos
Autores principales: Premkumar, M. H., Sule, G., Nagamani, S. C., Chakkalakal, S., Nordin, A., Jain, M., Ruan, M. Z., Bertin, T., Dawson, B., Zhang, J., Schady, D., Bryan, N. S., Campeau, P. M., Erez, A., Lee, B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2014
Materias:
Mucosal Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121640/
https://ncbi.nlm.nih.gov/pubmed/24904080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00403.2013
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