Argininosuccinate lyase in enterocytes protects from development of necrotizing enterocolitis

Necrotizing enterocolitis (NEC), the most common neonatal gastrointestinal emergency, results in significant mortality and morbidity, yet its pathogenesis remains unclear. Argininosuccinate lyase (ASL) is the only enzyme in mammals that is capable of synthesizing arginine. Arginine has several homeo...

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Bibliografski detalji
Glavni autori: Premkumar, M. H., Sule, G., Nagamani, S. C., Chakkalakal, S., Nordin, A., Jain, M., Ruan, M. Z., Bertin, T., Dawson, B., Zhang, J., Schady, D., Bryan, N. S., Campeau, P. M., Erez, A., Lee, B.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
Teme:
Mucosal Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121640/
https://ncbi.nlm.nih.gov/pubmed/24904080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00403.2013
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