Argininosuccinate lyase in enterocytes protects from development of necrotizing enterocolitis

Necrotizing enterocolitis (NEC), the most common neonatal gastrointestinal emergency, results in significant mortality and morbidity, yet its pathogenesis remains unclear. Argininosuccinate lyase (ASL) is the only enzyme in mammals that is capable of synthesizing arginine. Arginine has several homeo...

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Main Authors: Premkumar, M. H., Sule, G., Nagamani, S. C., Chakkalakal, S., Nordin, A., Jain, M., Ruan, M. Z., Bertin, T., Dawson, B., Zhang, J., Schady, D., Bryan, N. S., Campeau, P. M., Erez, A., Lee, B.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2014
主題:
Mucosal Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121640/
https://ncbi.nlm.nih.gov/pubmed/24904080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00403.2013
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