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Identification of the determinants of tRNA function and susceptibility to rapid tRNA decay by high-throughput in vivo analysis
Sequence variation in tRNA genes influences the structure, modification, and stability of tRNA; affects translation fidelity; impacts the activity of numerous isodecoders in metazoans; and leads to human diseases. To comprehensively define the effects of sequence variation on tRNA function, we devel...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117946/ https://ncbi.nlm.nih.gov/pubmed/25085423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.245936.114 |
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