Widespread temperature sensitivity and tRNA decay due to mutations in a yeast tRNA

Microorganisms have universally adapted their RNAs and proteins to survive at a broad range of temperatures and growth conditions. However, for RNAs, there is little quantitative understanding of the effects of mutations on function at high temperatures. To understand how variant tRNA function is af...

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Publicado no:RNA
Main Authors: Payea, Matthew J., Sloma, Michael F., Kon, Yoshiko, Young, David L., Guy, Michael P., Zhang, Xiaoju, De Zoysa, Thareendra, Fields, Stanley, Mathews, David H., Phizicky, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824359/
https://ncbi.nlm.nih.gov/pubmed/29259051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.064642.117
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