Concerning RNA-guided gene drives for the alteration of wild populations

Gene drives may be capable of addressing ecological problems by altering entire populations of wild organisms, but their use has remained largely theoretical due to technical constraints. Here we consider the potential for RNA-guided gene drives based on the CRISPR nuclease Cas9 to serve as a genera...

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Detaylı Bibliyografya
Asıl Yazarlar: Esvelt, Kevin M, Smidler, Andrea L, Catteruccia, Flaminia, Church, George M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2014
Konular:
Ecology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117217/
https://ncbi.nlm.nih.gov/pubmed/25035423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03401
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