Daisy-chain gene drives for the alteration of local populations

If they are able to spread in wild populations, CRISPR-based gene-drive elements would provide new ways to address ecological problems by altering the traits of wild organisms, but the potential for uncontrolled spread tremendously complicates ethical development and use. Here, we detail a self-exha...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Noble, Charleston, Min, John, Olejarz, Jason, Buchthal, Joanna, Chavez, Alejandro, Smidler, Andrea L., DeBenedictis, Erika A., Church, George M., Nowak, Martin A., Esvelt, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486765/
https://ncbi.nlm.nih.gov/pubmed/30940750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716358116
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