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Concerning RNA-guided gene drives for the alteration of wild populations

Gene drives may be capable of addressing ecological problems by altering entire populations of wild organisms, but their use has remained largely theoretical due to technical constraints. Here we consider the potential for RNA-guided gene drives based on the CRISPR nuclease Cas9 to serve as a genera...

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Autori principali: Esvelt, Kevin M, Smidler, Andrea L, Catteruccia, Flaminia, Church, George M
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117217/
https://ncbi.nlm.nih.gov/pubmed/25035423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03401
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