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Concerning RNA-guided gene drives for the alteration of wild populations

Gene drives may be capable of addressing ecological problems by altering entire populations of wild organisms, but their use has remained largely theoretical due to technical constraints. Here we consider the potential for RNA-guided gene drives based on the CRISPR nuclease Cas9 to serve as a genera...

詳細記述

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書誌詳細
主要な著者: Esvelt, Kevin M, Smidler, Andrea L, Catteruccia, Flaminia, Church, George M
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117217/
https://ncbi.nlm.nih.gov/pubmed/25035423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03401
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