Leukemogenesis Induced by an Activating β-catenin mutation in Osteoblasts

Cells of the osteoblast lineage affect homing, (1, 2) number of long term repopulating hematopoietic stem cells (HSCs) (3, 4), HSC mobilization and lineage determination and B lymphopoiesis (5-8). More recently osteoblasts were implicated in pre-leukemic conditions in mice (9, 10). Yet, it has not b...

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Autors principals: Kode, Aruna, Manavalan, John S., Mosialou, Ioanna, Bhagat, Govind, Rathinam, Chozha V., Luo, Na, Khiabanian, Hossein, Lee, Albert, Vundavalli, Murty, Friedman, Richard, Brum, Andrea, Park, David, Galili, Naomi, Mukherjee, Siddhartha, Teruya-Feldstein, Julie, Raza, Azra, Rabadan, Raul, Berman, Ellin, Kousteni, Stavroula
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116754/
https://ncbi.nlm.nih.gov/pubmed/24429522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12883
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