Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts

The bone marrow niche is thought to act as a permissive microenvironment required for emergence or progression of hematologic cancers. We hypothesized that osteoblasts, components of the niche involved in hematopoietic stem cell (HSC) function, influence the fate of leukemic blasts. We show that ost...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Krevvata, Maria, Silva, Barbara C., Manavalan, John S., Galan-Diez, Marta, Kode, Aruna, Matthews, Brya Grace, Park, David, Zhang, Chiyuan A., Galili, Naomi, Nickolas, Thomas L., Dempster, David W., Dougall, William, Teruya-Feldstein, Julie, Economides, Aris N., Kalajzic, Ivo, Raza, Azra, Berman, Ellin, Mukherjee, Siddhartha, Bhagat, Govind, Kousteni, Stavroula
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314530/
https://ncbi.nlm.nih.gov/pubmed/25139351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-517219
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