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Genetic Evidence Points to an Osteocalcin-independent Influence of Osteoblasts on Energy Metabolism

The skeleton has recently been shown to regulate glucose metabolism through an osteoblast-specific hormone, osteocalcin, which favors β-cell proliferation, insulin secretion, insulin sensitivity and energy expenditure. An implication of this finding is that a decrease in osteoblast numbers would com...

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Detalhes bibliográficos
Main Authors: Yoshikawa, Yoshihiro, Kode, Aruna, Xu, Lili, Mosialou, Ioanna, Silva, Barbara C., Ferron, Mathieu, Clemens, Thomas L., Economides, Aris N., Kousteni, Stavroula
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656486/
https://ncbi.nlm.nih.gov/pubmed/21557308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.417
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