FoxO1 is a Positive Regulator of Bone Formation by Favoring Protein Synthesis and Resistance to Oxidative Stress in Osteoblasts

Osteoporosis, a low bone mass disease, is associated with decreased osteoblast numbers and increased levels of oxidative stress in these cells. Since the FoxO family of transcription factors, confers stress resistance, we investigated their potential impact on skeletal integrity. We show here throug...

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Main Authors: Rached, Marie-Therese, Kode, Aruna, Xu, Lili, Yoshikawa, Yoshihiro, Paik, Ji-Hye, DePinho, Ronald A., Kousteni, Stavroula
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820405/
https://ncbi.nlm.nih.gov/pubmed/20142102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.01.001
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