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FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin
Serotonin is a critical regulator of bone mass, fulfilling different functions depending on its site of synthesis. Brain-derived serotonin promotes osteoblast proliferation, whereas duodenal-derived serotonin suppresses it. To understand the molecular mechanisms of duodenal-derived serotonin action...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3461930/ https://ncbi.nlm.nih.gov/pubmed/22945629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64906 |
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