FoxO1-Dependent Induction of Acute Myeloid Leukemia by Osteoblasts in Mice

Osteoblasts, the bone forming cells, affect self-renewal and expansion of hematopoietic stem cells (HSCs), as well as homing of healthy hematopoietic cells and tumor cells into the bone marrow. Constitutive activation of β-catenin in osteoblasts is sufficient to alter the differentiation potential o...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Leukemia
Main Authors: Kode, Aruna, Mosialou, Ioanna, Manavalan, Sanil J., Rathinam, Choza V., Friedman, Richard A., Teruya-Feldstein, Julie, Bhagat, Govind, Berman, Ellin, Kousteni, Stavroula
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691220/
https://ncbi.nlm.nih.gov/pubmed/26108693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.161
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki