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FoxO1 is a Positive Regulator of Bone Formation by Favoring Protein Synthesis and Resistance to Oxidative Stress in Osteoblasts

Osteoporosis, a low bone mass disease, is associated with decreased osteoblast numbers and increased levels of oxidative stress in these cells. Since the FoxO family of transcription factors, confers stress resistance, we investigated their potential impact on skeletal integrity. We show here throug...

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Hlavní autoři: Rached, Marie-Therese, Kode, Aruna, Xu, Lili, Yoshikawa, Yoshihiro, Paik, Ji-Hye, DePinho, Ronald A., Kousteni, Stavroula
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820405/
https://ncbi.nlm.nih.gov/pubmed/20142102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.01.001
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