Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts

The bone marrow niche is thought to act as a permissive microenvironment required for emergence or progression of hematologic cancers. We hypothesized that osteoblasts, components of the niche involved in hematopoietic stem cell (HSC) function, influence the fate of leukemic blasts. We show that ost...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Blood
Päätekijät: Krevvata, Maria, Silva, Barbara C., Manavalan, John S., Galan-Diez, Marta, Kode, Aruna, Matthews, Brya Grace, Park, David, Zhang, Chiyuan A., Galili, Naomi, Nickolas, Thomas L., Dempster, David W., Dougall, William, Teruya-Feldstein, Julie, Economides, Aris N., Kalajzic, Ivo, Raza, Azra, Berman, Ellin, Mukherjee, Siddhartha, Bhagat, Govind, Kousteni, Stavroula
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2014
Aiheet:
Myeloid Neoplasia
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314530/
https://ncbi.nlm.nih.gov/pubmed/25139351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-517219
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