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Leukemogenesis Induced by an Activating β-catenin mutation in Osteoblasts
Cells of the osteoblast lineage affect homing, (1, 2) number of long term repopulating hematopoietic stem cells (HSCs) (3, 4), HSC mobilization and lineage determination and B lymphopoiesis (5-8). More recently osteoblasts were implicated in pre-leukemic conditions in mice (9, 10). Yet, it has not b...
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4116754/ https://ncbi.nlm.nih.gov/pubmed/24429522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12883 |
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