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Relative importance of redox buffers GSH and NAD(P)H in age-related neurodegeneration and Alzheimer disease-like mouse neurons
Aging, a major risk factor in Alzheimer’s disease (AD), is associated with an oxidative redox shift, decreased redox buffer protection, and increased free radical reactive oxygen species (ROS) generation, probably linked to mitochondrial dysfunction. While NADH is the ultimate electron donor for man...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
BlackWell Publishing Ltd
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4116450/ https://ncbi.nlm.nih.gov/pubmed/24655393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12216 |
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