Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer’s Disease Neurons by Imposed External Cys/CySS Redox Shifts

Redox systems including extracellular cysteine/cystine (Cys/CySS), intracellular glutathione/oxidized glutathione (GSH/GSSG) and nicotinamide adenine dinucleotide reduced/oxidized forms (NADH/NAD(+)) are critical for maintaining redox homeostasis. Aging as a major risk factor for Alzheimer’s disease...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Dong, Yue, Sameni, Sara, Digman, Michelle A., Brewer, Gregory J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677822/
https://ncbi.nlm.nih.gov/pubmed/31375701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47582-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items