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Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer’s Disease Neurons by Imposed External Cys/CySS Redox Shifts
Redox systems including extracellular cysteine/cystine (Cys/CySS), intracellular glutathione/oxidized glutathione (GSH/GSSG) and nicotinamide adenine dinucleotide reduced/oxidized forms (NADH/NAD(+)) are critical for maintaining redox homeostasis. Aging as a major risk factor for Alzheimer’s disease...
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| Published in: | Sci Rep |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group UK
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6677822/ https://ncbi.nlm.nih.gov/pubmed/31375701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47582-x |
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