Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer’s Disease Neurons by Imposed External Cys/CySS Redox Shifts

Redox systems including extracellular cysteine/cystine (Cys/CySS), intracellular glutathione/oxidized glutathione (GSH/GSSG) and nicotinamide adenine dinucleotide reduced/oxidized forms (NADH/NAD(+)) are critical for maintaining redox homeostasis. Aging as a major risk factor for Alzheimer’s disease...

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Vydáno v:Sci Rep
Hlavní autoři: Dong, Yue, Sameni, Sara, Digman, Michelle A., Brewer, Gregory J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677822/
https://ncbi.nlm.nih.gov/pubmed/31375701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47582-x
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