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Age-Dependent Oxidation of Extracellular Cysteine/Cystine Redox State (E(h)(Cys/CySS)) in Mouse Lung Fibroblasts is Mediated by a Decline in Slc7a11 Expression

Aging is associated with progressive oxidation of the extracellular environment. The redox state of human plasma, defined by the concentrations of cysteine (Cys) and cystine (CySS), becomes more oxidized as we age. Recently, we showed that fibroblasts isolated from the lungs of young and old mice re...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Zheng, Yuxuan, Ritzenthaler, Jeffrey D., Burke, Tom J., Otero, Javier, Roman, Jesse, Watson, Walter H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5884717/
https://ncbi.nlm.nih.gov/pubmed/29458149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2018.02.026
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