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Global Metabolic Shifts in Age and Alzheimer’s Disease Mouse Brains Pivot at NAD(+)/NADH Redox Sites

Age and Alzheimer’s disease (AD) share some common features such as cognitive impairments, memory loss, metabolic disturbances, bioenergetic deficits, and inflammation. Yet little is known on how systematic shifts in metabolic networks depend on age and AD. In this work, we investigated the global m...

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Bibliografiske detaljer
Udgivet i:J Alzheimers Dis
Main Authors: Dong, Yue, Brewer, Gregory J.
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839468/
https://ncbi.nlm.nih.gov/pubmed/31356210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-190408
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