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Integrin-α5β1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation
Integrin α5β1 is essential for vascular development but it remains unclear precisely where and how it functions. Here, we report that deletion of the gene encoding the integrin-α5 subunit [Itga5] using the Pdgfrb-Cre transgenic mouse line, leads to oedema, haemorrhage and increased levels of embryon...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4113717/ https://ncbi.nlm.nih.gov/pubmed/24858485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.05.006 |
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