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Endothelial α5 and αv integrins cooperate in remodeling of the vasculature during development

Integrin cell adhesion receptors and fibronectin, one of their extracellular matrix ligands, have been demonstrated to be important for angiogenesis using functional perturbation studies and complete knockout mouse models. Here, we report on the roles of the α5 and αv integrins, which are the major...

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Dettagli Bibliografici
Autori principali: van der Flier, Arjan, Badu-Nkansah, Kwabena, Whittaker, Charles A., Crowley, Denise, Bronson, Roderick T., Lacy-Hulbert, Adam, Hynes, Richard O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889609/
https://ncbi.nlm.nih.gov/pubmed/20570943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.049551
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