Endothelial α5 and αv integrins cooperate in remodeling of the vasculature during development

Integrin cell adhesion receptors and fibronectin, one of their extracellular matrix ligands, have been demonstrated to be important for angiogenesis using functional perturbation studies and complete knockout mouse models. Here, we report on the roles of the α5 and αv integrins, which are the major...

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Bibliographic Details
Main Authors: van der Flier, Arjan, Badu-Nkansah, Kwabena, Whittaker, Charles A., Crowley, Denise, Bronson, Roderick T., Lacy-Hulbert, Adam, Hynes, Richard O.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2010
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889609/
https://ncbi.nlm.nih.gov/pubmed/20570943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.049551
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