Genetic Ablation of αv Integrins in Epithelial Cells of the Eyelid Skin and Conjunctiva Leads to Squamous Cell Carcinoma

Integrin-mediated cell adhesion and signaling events are essential for the proper development and homeostasis of most epithelial tissues. Dysregulation of integrin expression and function can cause abnormal epithelial cell proliferation and/or differentiation, contributing to the pathogenesis of mal...

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Detalhes bibliográficos
Main Authors: McCarty, Joseph H., Barry, Marc, Crowley, Denise, Bronson, Roderick T., Lacy-Hulbert, Adam, Hynes, Richard O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408432/
https://ncbi.nlm.nih.gov/pubmed/18467691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070700
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