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α5 and αv integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo

The RGD-binding α5 and αv integrins have been shown to be key regulators of vascular smooth muscle cell (vSMC) function in vitro. However, their role on vSMCs during vascular development in vivo remains unclear. To address this issue, we have generated mice that lack α5, αv or both α5 and αv integri...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Turner, Christopher J., Badu-Nkansah, Kwabena, Crowley, Denise, van der Flier, Arjan, Hynes, Richard O.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514387/
https://ncbi.nlm.nih.gov/pubmed/25670798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.117572
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