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Tie1 is required for lymphatic valve and collecting vessel development

Tie1 is a receptor tyrosine kinase with broad expression in embryonic endothelium. Reduction of Tie1 levels in mouse embryos with a hypomorphic Tie1 allele resulted in abnormal lymphatic patterning and architecture, decreased lymphatic draining efficiency, and ultimately, embryonic demise. Here we r...

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Podrobná bibliografie
Vydáno v:Dev Biol
Hlavní autoři: Qu, Xianghu, Zhou, Bin, Baldwin, H. Scott
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374493/
https://ncbi.nlm.nih.gov/pubmed/25576926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.12.021
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