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Tie1 is required for lymphatic valve and collecting vessel development
Tie1 is a receptor tyrosine kinase with broad expression in embryonic endothelium. Reduction of Tie1 levels in mouse embryos with a hypomorphic Tie1 allele resulted in abnormal lymphatic patterning and architecture, decreased lymphatic draining efficiency, and ultimately, embryonic demise. Here we r...
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| Publicado no: | Dev Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4374493/ https://ncbi.nlm.nih.gov/pubmed/25576926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.12.021 |
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