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Loss of Flow Responsive Tie1 Results in Impaired Aortic Valve Remodeling
The mechanisms regulating endothelial cell response to hemodynamic forces required for heart valve development, especially valve remodeling, remain elusive. Tie1, an endothelial specific receptor tyrosine kinase, is up-regulated by oscillating shear stress and is required for lymphatic valve develop...
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| Publicado en: | Dev Biol |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8269330/ https://ncbi.nlm.nih.gov/pubmed/31319059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2019.07.011 |
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