GATA2 is required for lymphatic vessel valve development and maintenance

Heterozygous germline mutations in the zinc finger transcription factor GATA2 have recently been shown to underlie a range of clinical phenotypes, including Emberger syndrome, a disorder characterized by lymphedema and predisposition to myelodysplastic syndrome/acute myeloid leukemia (MDS/AML). Desp...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kazenwadel, Jan, Betterman, Kelly L., Chong, Chan-Eng, Stokes, Philippa H., Lee, Young K., Secker, Genevieve A., Agalarov, Yan, Demir, Cansaran Saygili, Lawrence, David M., Sutton, Drew L., Tabruyn, Sebastien P., Miura, Naoyuki, Salminen, Marjo, Petrova, Tatiana V., Matthews, Jacqueline M., Hahn, Christopher N., Scott, Hamish S., Harvey, Natasha L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563742/
https://ncbi.nlm.nih.gov/pubmed/26214525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78888
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