Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow

The atypical cadherin FAT4 has established roles in the regulation of planar cell polarity and Hippo pathway signaling that are cell context dependent. The recent identification of FAT4 mutations in Hennekam syndrome, features of which include lymphedema, lymphangiectasia, and mental retardation, un...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Betterman, Kelly L., Sutton, Drew L., Secker, Genevieve A., Kazenwadel, Jan, Oszmiana, Anna, Lim, Lillian, Miura, Naoyuki, Sorokin, Lydia, Hogan, Benjamin M., Kahn, Mark L., McNeill, Helen, Harvey, Natasha L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260025/
https://ncbi.nlm.nih.gov/pubmed/32182215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99027
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