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Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow
The atypical cadherin FAT4 has established roles in the regulation of planar cell polarity and Hippo pathway signaling that are cell context dependent. The recent identification of FAT4 mutations in Hennekam syndrome, features of which include lymphedema, lymphangiectasia, and mental retardation, un...
Gardado en:
| Publicado en: | J Clin Invest |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7260025/ https://ncbi.nlm.nih.gov/pubmed/32182215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99027 |
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