Bicarbonate-sensitive soluble and transmembrane adenylyl cyclases in peripheral chemoreceptors

Stimulation of the carotid body (CB) chemoreceptors by hypercapnia triggers a reflex ventilatory response via a cascade of cellular events, which includes generation of cAMP. However, it is not known if molecular CO(2)/HCO(3)(−) and/or H(+) mediate this effect and how these molecules contribute to c...

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Main Authors: Nunes, Ana R., Holmes, Andrew P.S., Sample, Vedangi, Kumar, Prem, Cann, Martin J., Monteiro, Emília C., Zhang, Jin, Gauda, Estelle B.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112945/
https://ncbi.nlm.nih.gov/pubmed/23727159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resp.2013.05.013
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