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Soluble adenylyl cyclase mediates bicarbonate-dependent corneal endothelial cell protection
Cyclic AMP produced from membrane receptor complex bound adenylyl cyclases is protective in corneal endothelial cells (CEC). CEC also express soluble adenylyl cyclase (sAC), which is localized throughout the cytoplasm. When activated by HCO(3)(−), cAMP concentration ([cAMP]) increases by ∼50%. Here...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3043628/ https://ncbi.nlm.nih.gov/pubmed/21123735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00314.2010 |
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