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[HCO(3)(-)]-regulated expression and activity of soluble adenylyl cyclase in corneal endothelial and Calu-3 cells
BACKGROUND: Bicarbonate activated Soluble Adenylyl Cyclase (sAC) is a unique cytoplasmic and nuclear signaling mechanism for the generation of cAMP. HCO(3)(- )activates sAC in bovine corneal endothelial cells (BCECs), increasing [cAMP] and stimulating PKA, leading to phosphorylation of the cystic fi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC411047/ https://ncbi.nlm.nih.gov/pubmed/15117409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6793-4-8 |
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