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CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70

Exposure of cells to various stresses often leads to the induction of a group of proteins called heat shock proteins (HSPs, molecular chaperones)(1,2). Hsp70 is one of the most highly inducible molecular chaperones, but its expression must be maintained at low levels under physiological conditions t...

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書誌詳細
主要な著者: Qian, Shu-Bing, McDonough, Holly, Boellmann, Frank, Cyr, Douglas M., Patterson, Cam
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112096/
https://ncbi.nlm.nih.gov/pubmed/16554822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04600
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