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CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70

Exposure of cells to various stresses often leads to the induction of a group of proteins called heat shock proteins (HSPs, molecular chaperones)(1,2). Hsp70 is one of the most highly inducible molecular chaperones, but its expression must be maintained at low levels under physiological conditions t...

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Detalhes bibliográficos
Main Authors: Qian, Shu-Bing, McDonough, Holly, Boellmann, Frank, Cyr, Douglas M., Patterson, Cam
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112096/
https://ncbi.nlm.nih.gov/pubmed/16554822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04600
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