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CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70
Exposure of cells to various stresses often leads to the induction of a group of proteins called heat shock proteins (HSPs, molecular chaperones)(1,2). Hsp70 is one of the most highly inducible molecular chaperones, but its expression must be maintained at low levels under physiological conditions t...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4112096/ https://ncbi.nlm.nih.gov/pubmed/16554822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04600 |
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