Stress-dependent Daxx-CHIP Interaction Suppresses the p53 Apoptotic Program

Our previous studies have implicated CHIP (carboxyl terminus of Hsp70-interacting protein) as a co-chaperone/ubiquitin ligase whose activities yield protection against stress-induced apoptotic events. In this report, we demonstrate a stress-dependent interaction between CHIP and Daxx (death domain-a...

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Detalhes bibliográficos
Main Authors: McDonough, Holly, Charles, Peter C., Hilliard, Eleanor G., Qian, Shu-bing, Min, Jin-Na, Portbury, Andrea, Cyr, Douglas M., Patterson, Cam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742829/
https://ncbi.nlm.nih.gov/pubmed/19465479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.011767
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